Please be more specific than "various dictionaries on the Yahoo site". I think they are identified.

This change brings it more into line with the Daijirin/GG5 entries. I take the point about rolling sense 3 into sense 1. I guess it works.

Including (and leading) with just "house" is wrong.

Looking at the various dictionaries on the Yahoo site, none has "house-like building" as a separate sense. I think it's definitely part of 
sense 1 and I don't think "house" absolutely has to be a dwelling either ("house of prayer", "movie house", "the local fish house", "a 
house of prostitution" - all examples from English dictionary entries for "house") but either way it's definitely not a separate sense.

@@ -19 +18,0 @@
-<gloss>house</gloss>
@@ -21,0 +21 @@
+<gloss>single building</gloss>
@@ -28,4 +27,0 @@
-<sense>
-<pos>&n;</pos>
-<gloss>building resembling a house, occupied by a single business (e.g. restaurant)</gloss>
-</sense>

OK, let's make that clear.

@@ -26,0 +26,1 @@
+<gloss>house in isolated location</gloss>

According to some of the sources I found, "isolated house" really means 
that the house is in a place where there aren't any other houses at all 
– not simply separated by a few metres from the neighbours like your 
house, Jim :-)
.
For example, Meikyo says:
1) あたりに家がない所に、一つだけぽつんと建っている家。「野中の一軒家」
2) ...

長屋 is not really an antonym.
I think "building resembling a house, ...." is really another sense.
Splitting off "isolated house" into its own sense seems odd to me, but then I live in an environment where all most houses are detached/isolated.

@@ -19,1 +19,0 @@
-<xref type="ant" seq="1797650">長屋</xref>
@@ -23,1 +22,0 @@
-<gloss>building resembling a house, occupied by a single business (e.g. restaurant)</gloss>
@@ -29,0 +27,4 @@
+<sense>
+<pos>&n;</pos>
+<gloss>building resembling a house, occupied by a single business (e.g. restaurant)</gloss>
+</sense>